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產(chǎn)品中心抗體/抗原病理/IHC抗體S0B2374CK7/8 Recombinant Rabbit mAb (SDT-P006)
產(chǎn)品型號：S0B2374
更新時間：2025-10-11
廠商性質(zhì)：生產(chǎn)廠家
訪問量：478
服務熱線15855403091
產(chǎn)品分類
Cytokeratin 7/8 （CK7/8） proteins are intermediate filament proteins that play crucial roles in maintaining the structural integrity and function of epithelial cells. CK7, also known as sacolectin, is a type II cytokeratin typically found in glandular epithelia and transitional epithelium, including their associated tumors. CK8 is a type I cytokeratin that pairs with CK7 to form heterodimers, which are essential for the stability and function of the cytoskeleton in epithelial cells. These proteins are widely expressed in various organs and tissues, such as the thyroid, lung, female reproductive organs, upper digestive tract, and head and neck region. In pathology, CK7/8 are valuable markers for distinguishing epithelial tumors and identifying their origins. For example, CK7 is often positive in tumors of the breast, lung, and female reproductive system, while CK8 helps in further characterizing these tumors. Their expression patterns can also provide insights into the differentiation and behavior of tumor cells.
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