產(chǎn)品中心
當(dāng)前位置:首頁
產(chǎn)品中心
抗體/抗原
病理/IHC抗體
S0B2367PMAFA Recombinant Rabbit mAb,PBS Only (SDT-2040-6)

產(chǎn)品型號:S0B2367P
更新時(shí)間:2025-10-11
廠商性質(zhì):生產(chǎn)廠家
訪問量:267
服務(wù)熱線15855403091
產(chǎn)品分類
The MAFA protein (Musculoaponeurotic Fibrosarcoma Oncogene Homolog A) is a member of the basic leucine zipper (bZIP) transcription factor family, primarily expressed in pancreatic β-cells, the retina, and lymphocytes. It plays a critical role in regulating the transcription of the insulin gene (INS) by binding to the C1 element in the insulin gene promoter region, thereby promoting insulin synthesis and secretion to maintain glucose homeostasis. The expression and activity of MAFA are regulated by various factors, including glucose concentration, cytokines, and oxidative stress. In diabetes research, dysfunction of MAFA is closely associated with β-cell dysfunction and impaired insulin secretion, making it a potential therapeutic target. Additionally, MAFA also plays important roles in retinal development and immune regulation.
關(guān)注公眾號
Copyright © 2026杭州斯達(dá)特生物科技有限公司 All Rights Reserved 工信部備案號:
技術(shù)支持:化工儀器網(wǎng) 管理登錄 sitemap.xml