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產(chǎn)品中心抗體/抗原偶聯(lián)抗體S0B1837CD8α Mouse mAb (Alexa Fluor? 594 Conjugate) (SDT-1036-34)
產(chǎn)品型號：S0B1837
更新時間：2025-10-11
廠商性質(zhì)：生產(chǎn)廠家
訪問量：206
服務(wù)熱線15855403091
產(chǎn)品分類
CD8α is a crucial subunit of the CD8 co-receptor complex found on the surface of cytotoxic T lymphocytes （CTLs） and some natural killer （NK） cells. It is a 32 kDa glycoprotein that can form either an α/β heterodimer or an α/α homodimer with CD8β. CD8α plays a vital role in immune responses by binding to MHC class I molecules on antigen-presenting cells （APCs）, facilitating the recognition and destruction of infected or abnormal cells. This interaction helps activate the T cell receptor （TCR） complex, recruiting the LCK kinase and initiating multiple signaling pathways. Additionally, CD8αα homodimers are found on intraepithelial lymphocytes （IELs）, which protect mucosal surfaces like the intestinal barrier.
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