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產(chǎn)品中心抗體/抗原病理/IHC抗體S0B2283Claudin 5 Recombinant Rabbit mAb (SDT-R322)
產(chǎn)品型號：S0B2283
更新時間：2025-10-10
廠商性質(zhì)：生產(chǎn)廠家
訪問量：227
服務熱線15855403091
產(chǎn)品分類
Claudin-5 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction （TJ） strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Claudin-5 is an endothelial cell-specific component of TJ strands. It has been used as a marker for endothelial lesions. Claudin-5 is also found in bronchial and lung epithelial cells. In tumors, Claudn-5 expression has been found in lung adenocarcinoma and squamous carcinoma. Strong membranous expression of claudin5 and claudin7 differentiates pancreatic solid papillary neoplasm from pancreatoblastoma, acinar cell and endocrine tumors.
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