Alexa Fluor? 647 Mouse Anti-Human CD47 Antibody (S-823-72)

產(chǎn)品型號(hào)：S0B5421

更新時(shí)間：2025-10-09

廠商性質(zhì)：生產(chǎn)廠家

訪問量：94

服務(wù)熱線

15855403091

立即咨詢

產(chǎn)品分類

PRODUCT CLASSIFICATION

抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對(duì)抗體病理/IHC抗體

查看全部產(chǎn)品

相關(guān)文章

流式抗體封閉：如何有效避免實(shí)驗(yàn)中的假陽性結(jié)果？

成纖維細(xì)胞生長(zhǎng)因子受體2b抗體：從基礎(chǔ)研究到臨床轉(zhuǎn)化的前沿探索

腸道黏蛋白 MUC2：從黏液屏障到疾病開關(guān)的雙重身份解碼

TDP-43與漸凍癥：守護(hù)or背叛？

產(chǎn)品介紹

CD47, also known as integrin-associated protein, is a ubiquitously expressed cell surface receptor that belongs to the immunoglobulin superfamily. It is widely known for its role in preventing macrophage-mediated phagocytosis by interacting with signal regulatory protein alpha （SIRPα） on phagocytic cells. This “don’t eat me" signal is crucial for the survival of healthy cells, but cancer cells often overexpress CD47 to evade immune attack. In addition to its role in immune regulation, CD47 is involved in various cellular processes, including cell adhesion, migration, and the regulation of autophagy and cell death. For instance, it can regulate the migration of immune cells like neutrophils and dendritic cells, and its interaction with thrombospondin-1 （TSP-1） can induce apoptosis in certain cell types. Due to its significant role in cancer immunotherapy, CD47 has become an important target for developing new therapeutic strategies.

上一個(gè)：S0B5415FITC Rat Anti-Mouse CD185 Antibody (S-R600)