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產(chǎn)品中心抗體/抗原流式抗體S0B5400FITC Rat Anti-Mouse CD34 Antibody (S-R599)
產(chǎn)品型號：S0B5400
更新時間：2025-10-09
廠商性質：生產(chǎn)廠家
訪問量：106
服務熱線15855403091
產(chǎn)品分類
CD34 is a transmembrane phosphoglycoprotein first identified on hematopoietic stem and progenitor cells. It is a member of the sialomucin family, with other members including podocalyxin and endoglycan. This protein functions primarily as an adhesion molecule, involved in cell-cell adhesion and cell-matrix interactions. It enhances the proliferation of progenitor cells and blocks cell differentiation, which is crucial for maintaining a pool of immature cells that can develop into various specialized cells as needed. CD34 also plays a role in immune system regulation, particularly in the adhesion of lymphocytes to blood vessel walls. Besides hematopoietic cells, CD34 is expressed on endothelial cells, fibrocytes, muscle satellite cells, and some cancer stem cells. Its expression has been utilized for the selection and enrichment of hematopoietic stem cells for bone marrow transplants.
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