Mouse Anti-Rat CD43 Antibody (S-R632)

產(chǎn)品型號：S0B5255

更新時間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

訪問量：102

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ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

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產(chǎn)品介紹

CD43, also known as leukosialin or sialophorin, is a type I transmembrane glycoprotein abundantly expressed on the surface of most hematopoietic cells, with the exception of erythrocytes and resting B cells. It has a heavily glycosylated extracellular domain and a cytoplasmic tail. CD43 plays multiple roles in immune responses, including regulation of T-cell activation, proliferation, and cytokine production. It also interacts with ERM proteins （ezrin, radixin, moesin） via a specific sequence in its cytoplasmic tail, which is important for its function in cell adhesion and migration. Additionally, CD43 has been implicated in various biological processes such as leukocyte migration, immune cell signaling, and even tumor progression. Its expression and function can vary depending on the cell type and the specific immune context.

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