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產(chǎn)品中心抗體/抗原流式抗體S0B5236Rat Anti-Mouse CD104 Antibody (S-R716)
產(chǎn)品型號：S0B5236
更新時間：2025-10-08
廠商性質(zhì)：生產(chǎn)廠家
訪問量：88
服務(wù)熱線15855403091
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Integrin beta 4 （ITGB4） is a key subunit of the integrin family, primarily functioning as a receptor for laminins and often associating with the alpha 6 subunit to form the α6β4 integrin complex. This transmembrane glycoprotein receptor plays a crucial role in mediating cell-matrix adhesion and signaling, which regulates gene expression, cell growth, and migration. ITGB4 is particularly important in maintaining the stability of hemidesmosomes, which anchor epithelial cells to the basement membrane. Additionally, its expression and activity are implicated in various biological processes, including wound healing, tissue integrity, and cancer progression. Abnormal mutations or dysregulation of ITGB4 have been associated with diseases such as epidermolysis bullosa with pyloric atresia.
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