Biotin Rabbit Anti-Mouse NK1.1/CD161 Antibody (S-428-32)

產(chǎn)品型號(hào)：S0B5088

更新時(shí)間：2025-10-08

廠商性質(zhì)：生產(chǎn)廠家

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抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對(duì)抗體病理/IHC抗體

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產(chǎn)品介紹

NK1.1/CD161, also known as KLRB1 or NKR-P1A, is a type II transmembrane C-type lectin-like receptor expressed as a disulfide-linked homodimer on the cell membrane. It is predominantly found on the majority of natural killer （NK） cells and subsets of peripheral T cells, including both CD4+ and CD8+ T cells, particularly those with a "memory" antigenic phenotype. The expression of CD161 is specifically upregulated by IL-12 and is associated with the cytotoxic function of CD16+ NK cells. Functionally, CD161 plays a role in modulating the activation and proliferation of NK cells, inducing interferon-γ production, and releasing cytotoxic granules. When CD161 binds to its ligand LLT1, it inhibits NK cell cytotoxicity and cytokine secretion.

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