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產(chǎn)品中心抗體/抗原流式抗體S0B1716Biotin Mouse Anti-Human CD19 Antibody (S-R503-2)
產(chǎn)品型號：S0B1716
更新時間：2025-10-08
廠商性質(zhì)：生產(chǎn)廠家
訪問量：91
服務熱線15855403091
產(chǎn)品分類
CD19 is a transmembrane glycoprotein and a member of the immunoglobulin superfamily, predominantly expressed on B lymphocytes, making it a significant marker for B cell development and function. It plays a crucial role in B cell activation, signal transduction, and growth regulation. CD19 is involved in the B cell receptor （BCR） signaling pathway, enhancing B cell activation thresholds and proliferation. In the context of disease, CD19 is highly expressed in most B cell malignancies, including acute lymphoblastic leukemia （ALL）, chronic lymphocytic leukemia （CLL）, and B cell lymphomas, making it a promising target for immunotherapy. The CD19 molecule is also implicated in autoimmune and immunodeficiency disorders, with mutations in CD19 associated with severe immunodeficiency syndromes characterized by reduced antibody production.
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