Alexa Fluor? 488 Mouse Anti-Human CD123 Antibody (S-R442)

產(chǎn)品型號：S0B1617

更新時間：2025-10-07

廠商性質(zhì)：生產(chǎn)廠家

訪問量：97

服務(wù)熱線

15855403091

立即咨詢

產(chǎn)品分類

PRODUCT CLASSIFICATION

抗體/抗原

ELISA試劑盒抗體試劑盒二抗試劑盒二抗其它流式抗體瓊脂糖/磁珠偶聯(lián)抗體抗Payload抗體泛修飾抗體標(biāo)簽/內(nèi)參抗體功能性抗體 Biosimilar抗體偶聯(lián)抗體配對抗體病理/IHC抗體

查看全部產(chǎn)品

相關(guān)文章

流式抗體封閉：如何有效避免實驗中的假陽性結(jié)果？

成纖維細(xì)胞生長因子受體2b抗體：從基礎(chǔ)研究到臨床轉(zhuǎn)化的前沿探索

腸道黏蛋白 MUC2：從黏液屏障到疾病開關(guān)的雙重身份解碼

TDP-43與漸凍癥：守護(hù)or背叛？

產(chǎn)品介紹

The CD123 protein, also known as the Interleukin-3 receptor subunit alpha （IL-3RA） or CD123, is a crucial component of the interleukin-3 （IL-3） receptor complex and belongs to the Type I cytokine receptor family, specifically the Class 5 subfamily. CD123 serves as the high-affinity receptor for IL-3, forming a heterodimeric receptor complex with the β chain （CSF2RB）. This protein mediates the stimulatory effects of IL-3 on the proliferation and differentiation of various hematopoietic cells, including pluripotent hematopoietic stem cells and lineage-committed cells. CD123 is expressed on normal plasmacytoid dendritic cells, basophils, monocytes, and eosinophils, and is overexpressed in various hematologic malignancies. In clinical research, the expression of CD123 is associated with chemotherapy resistance and high-risk genetic alterations in certain leukemias, such as acute myeloid leukemia （AML）.

上一個：S0B1618Alexa Fluor? 488 Mouse Anti-Human Integrin beta1/CD29 Antibody (S-933-228)